Brintellix® (vortioxetine) combines effective and sustained relief from major depressive disorder (MDD) symptoms* with a well tolerated profile (†1-7)

^{*As measured by MADRS.}

Brintellix^® is generally well tolerated ¹

BRINTELLIX IS WELL TOLERATED

1-1

_{Adverse events that occurred in Brintellix^® treated patients in the course of the MDD short-term, placebo-controlled studies with an incidence ≥10% were headache and nausea. Other adverse events include: vomiting; diarrhoea; constipation; dizziness; generalised pruritus; hyponatraemia.¹ For full information please see the Product Information.}

_{CSFQ-14, change in sexual functioning questionnaire short form; DESS, discontinuation-emergent signs and symptoms; MDD, major depressive disorder; MOAI, monoamine oxidase inhibitor; SNRI, serotonin–norepinephrine reuptake inhibitor; SSRI, selective serotonin reuptake inhibitor; TEAE, treatment-emergent adverse event.}

References

1. Brintellix® Australian Approved Product Information.
2. Alvarez E, et al. Int J Neuropsychopharmacol 2012; 15:589-600.
3. Montgomery SA, et al. Hum Psychopharmacol Clin Exp 2014; 29(5):470-482.
4. Boulenger JP, et al. J Psychopharmacol 2012; 26(11):1408-1416.
5. Katona C, et al. Int Clin Pyschopharmacol 2012; 27(4):215-223.
6. Cao B, et al. Front Psychiatry 2019; 10: 17.
7. Christensen MC et al. CNS Spectr 2021; 1-8.
8. Jacobsen PL, et al. J Sex Med 2015; 12(10): 2036-2048.
9. Llorca PM et al. Curr Med Res Opin 2014; 12: 2589-2606.
10. Clayton AH et al. Expert Opin Drug Saf 2014; 13(10): 1361-1374.
11. Thase ME et al. Eur Neuropsychopharmacol 2017; 8: 773-781.
12. Baldwin DS et al. J Psychopharmacol 2016a; 30(3): 242-252.
13. Chen G et al. Clin Pharmacokinet 2018; 57: 673-686.
14. Hosenbocus S, Chahal R. J Can Acad Child Adolesc Psychiatry 2011; 20: 60-67.
15. Mahableshwarkar AR et al. Psychopharmacology (Berl) 2015; 232: 2061-2070.
16. Fava GA et al. Psychosom 2015; 84: 72–81.

^{Internal ID: AU-BRIN-0479. September 2022.}

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Brintellix

Brintellix® (vortioxetine) combines effective and sustained relief from major depressive disorder (MDD) symptoms* with a well tolerated profile (†1-7)

Brintellix^® is generally well tolerated ¹

References

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Brintellix® (vortioxetine) combines effective and sustained relief from major depressive disorder (MDD) symptoms* with a well tolerated profile (†1-7)

Brintellix® is generally well tolerated 1

References

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Brintellix^® is generally well tolerated ¹